Cynthia A. Janak
June 29, 2010
The truth about the HPV vaccines or what they do not want you to know (Part 6)
By Cynthia A. Janak

For those of you who have come to this article for the first time I would suggest that you start at the beginning of this series. All the information that was presented to the FDA on March 12th of 2010 starts with the information about HPV. My feelings are that it is best to get the whole story and not just part. Anyway, I want to thank you for being here.

Before I continue I want to share with you something new that I found on the FDA website. Boy, I find such things when I am looking for something else. It could be the hand of God leading me to this stuff. But anyway on to what I found.

On May 19th of 2008 the FDA had a meeting with the Infectious Disease Society of America (IDSA). The title of the presentation was "Immunization Before the Next Pandemic? Risks, Benefits and Pathways. The presenter was Jesse L. Goodman, MD, MPH, Director, Center for Biologics Evaluation and Research, IDSA, Washington, DC.(1)

I found the whole presentation interesting and I wish that they would have had the whole transcript of this presentation but the slides tell the story. The slides that caught my interest were slides 32 and 33 that are titled "Detecting Rare Adverse Events: some simple math". Dr. Goodman mentions the impracticality of large trials. This is what he states on the slide. (I want to note here that the presentation was about a pandemic but this section mentions large clinical trials.)

Even impractically large trials will often fail to confirm small increases in events which may be significant when applied to a large population

What this tells me is that they know that the adverse events of a drug or vaccine are not truly known until given to a large population. This brings to mind what Dr. Diane Harper said about the HPV vaccines. "Giving it to 11-year-olds is a great big public health experiment," (2)

•Examples:

— Confirming an increase in an event from ~1/10,000 to 2/10,000 would need ~ 314,000 subjects yet this difference could result in >300 SAEs in a birth cohort of > 3 million

— Magnify that population to that of a country or region of 60 million and there could be 6000 such events

•Low compared to a 1 % death rate from a pandemic, or 600,000 in 60 million — but what if no pandemic, or a lower death rate?

This problem could be even more challenging if an adverse event is more common, poorly defined or not temporally related.

— e.g. 768 baseline deaths/100,000 age <1. To detect an increase in to 798/100,000 (or >1200 attributable deaths/US birth cohort); might need 2.6 million subjects


Using this analogy we could say that if 73.3% of the participants had a "New Medical Condition" then out of 1,000,000 vaccinated you could have 733,000 young people affected in some way. Wow that just makes my head spin. Whoa!

I just had to inform you of this new finding by me but old to the FDA and IDSA.

Now, on to this part of the story.

As I promised I am going to focus on the question: "I am 18 and my friends and I received the Gardasil series. Why do I have an autoimmune disorder and they do not?"

In the three years we have been researching Gardasil we have been in contact with hundreds of parents via phone, personal email and message boards.

What we determined was that there are three groups of young women that could be affected when they receive this vaccination series. They are:

• Athletic

• Overweight

• Vaccination during Paramenstrum

Our research also found that there were three recurring reasons why they had the potential to be affected; family history of allergies, elevated testosterone levels and hormone cycles."

Early on in our investigations we found that there was a common denominator between the Gardasil Girls and that was a family history of allergies. This was discovered due to the many conversations, emails, blog and message board entries when parents where asked about this was a resounding YES.

This was very interesting to us because a poll was done of the Autism community and the parents that responded when posed the question about a family history of allergies were also a resounding YES.

What we have been able to deduce because of scientific studies we have found is that these young girls probably had elevated levels of histamine receptors to start with. Histamine is what causes our allergic reactions. If these girls had allergies then there was a good chance of them having elevated levels of IgE also. This will be further explored in a future article in this series because of all the scientific studies and articles that were found on the subject.

What I am going to focus on today are the athletic or very active individuals.

The first group of females affected from the Gardasil vaccine is those who were athletic.

We have been able to ascertain that the majority of the girls injured or who died was mainly athletes with a high GPA. Many of the girls had no pre-existing conditions and some had a family history of medical issues.

According to our research these athletic females would have had a higher 24 hour level of testosterone secretion. Testosterone levels in female athletes increases by 24% pre-event and 49% during the competition. This further emphasizes that the higher level of testosterone could play a vital role in adverse events reported after vaccination by athletic females.

This was taken from the Journal of Clinical Endocrinology & Metabolism. "We found that 24-h profiles of testosterone, LH, and PRL were positively correlated and cortisol negatively correlated with the number of menstruations during the last year in these athletes. However, the endocrine profiles in amenorrheic and oligomenorrheic athletes were apparently different. Amenorrehic athletes displayed a hormonal pattern in agreement with hypothalamic inhibition. In contrast, oligomenorrheic athletes had higher 24-h secretion of testosterone than all other groups." (3)

We also found this with regards to the importance of testosterone in female athletes.

The pre-event rise in males averages nine percent whereas in females it increases by twenty-four percent. During the competition itself women increase their testosterone production by forty-nine percent while in males it increases on average fifteen percent.

"We are not sure why women's testosterone elevation prior to competition is so much greater than it is in men. It is probably due to the fact that every day levels of testosterone are four times higher in men than they are in women. To effectively meet the challenge a higher production rate may be necessary," explains Dr. Alan Booth, Distinguished Professor of Sociology, Human Development and Family Studies, and Demography at Pennsylvania State University.

"Among women, pre-game testosterone increases were significantly correlated with reports of being focused just prior to the game, just as it is associated with arousal in men," Booth says. "Unlike pre-game increases in men, the pre-game increase among women was unrelated to the perceptions of how easy or difficult the opponent was thought to be prior to the game. Men seem to adjust their pre-game rise to the perceived strength of the opponent."
(4)

I know you are wondering how the Autism community fits in here. Well I am about to tell you.

One of the know facts in the Autism community is that 4 out of 5 children affected are male. Another known fact is that Autism is at a rate of 1 out of every 100 children are diagnosed with this. The findings of higher levels of testosterone have been written about in the media.

Here are some excerpts from Time magazine under their Health & Science category. The title of the article is "A Link Between Autism and Testosterone?" by Eben Harrell, January 15th of 2009. (5) This is what Simon Baron-Cohen has to say taken from the article.

A researcher who describes autism as a condition of the "extreme male brain" says fetuses exposed in the womb to high levels of the male hormone testosterone are more likely than others to develop autistic traits as children.

Simon Baron-Cohen, director of Cambridge University's Autism Research Centre, has shown in past research that men are more likely than women to score low on tests of empathy but high on tests of "systemizing" — recognizing rules and patterns — characteristics that, in the extreme, define autism. That's what led Baron-Cohen to regard the disorder — which is about three to four times as prevalent in boys as in girls — as one of the extreme male brain and to search for a link to male hormones. (See "The Year in Medicine: From A to Z.")

In his new paper, published on Monday in the British Journal of Psychology, Baron-Cohen studied 235 pairs of mothers and children over eight years, periodically giving the children questionnaires designed to measure autistic traits. None of the children in the study received an autism diagnosis, but Baron-Cohen found that those who had been exposed to higher testosterone levels in the womb — measured via amniocentesis during pregnancy — had a greater chance of displaying autism-associated traits such as poor social skills, imagination and empathy and high aptitude in certain memory-retention exercises


What I also found interesting is what Dr. James B. Adams had to say. I am going to highlight what I found (this will be discussed in the last article of this series.)

Researchers who are more sympathetic to Baron-Cohen's work, like James B. Adams, a professor at Arizona State University's School of Materials, do not discount the theory that testosterone exposure is linked to autism but believe the association may be mediated by other potential causes. For his part, Adams believes autism is related to exposure to mercury — a controversial charge that most research has failed to support — and, Adams says, elevated testosterone levels are linked to the depletion of glutathione, a substance in the body that protects it from toxic metals. "So Baron-Cohen's work ties in with the mercury hypothesis," Adams says.

This article had such a wealth of information that I hope I do not get into trouble for referencing so much of it.

Not all experts agree. Laurent Mottron, a professor of psychiatry at the University of Montreal who wrote an accompanying review of Baron-Cohen's study, told TIME that Baron-Cohen's study, including the questionnaires used to measure autistic traits, presented major "logical and factual flaws." Because the children in the study were normally developing rather than autistic, the study showed only that exposure to testosterone was associated with typically male cognition, not a disorder.

In an e-mail, Mottron wrote, "Baron-Cohen used a questionnaire which scores high in autistics. This questionnaire also scores higher in [nonautistic] men than in women. This only demonstrates that the autism questionnaire is a very weak and broad instrument, which is unable to differentiate autism and male characteristics. It does not demonstrate that autism is linked to testosterone."


Don't you just love these scientists? I have read all kinds of studies about testosterone and none of them where able to think outside of their own individual specialty box. What I have found in all my research is that no one is looking for newly diagnosed Autism in older adult males. Why you may ask? My opinion is that it just does not exist. They have researched testosterone in regards to stroke and Alzheimer's but not Autism.

Something got my curiosity going in the article I quoted and that was the reference of "elevated testosterone levels are linked to the depletion of glutathione." I found all kinds of scientific studies in regards to glutathione. Interesting reading I must say but when I tried to put the studies into a form for you to understand was incredibly difficult. Well, that is scientists for you. Even their conclusions which are usually the easiest part to understand was not working for me. So I kept on searching.

I did find a website and I am going to say that I usually do not use this type of site and I will not promote the product on the site but the information was really good with studies cited. It is pretty easy to understand the role that glutathione plays in the body.

I was wondering how this would relate to athletes. I got my answer. "Glutathione is always in great demand and is rapidly consumed when we experience any sort of emotional or physical stress, fatigue and even moderate exercise." (6) So there is a good chance that the Gardasil girls because they are athletes not only have higher levels of testosterone but lower levels of glutathione.

As I was reading the article presented on the website I came to a section called "Food for the Blood." This is what they say, "Glutathione plays a central role in the proper function of the white blood cells. Dr. Bustavo Bounous, a leading glutathione expert, says, 'The limiting factor in the proper activity of our lymphocytes (the white blood cells) is the availability of glutathione.' In other words, healthy growth and activity of the white blood cells depends upon glutathione's availability. Put simply, glutathione is 'food' for the white blood cells." (6)

This reminded me of a question posed about Gardasil causing anemia a couple of weeks ago. So that got me to thinking about vaccination causing stress to the body and the chemicals in the vaccines. So of course I had to dig deeper and find out if it were possible for a vaccination to cause anemia.

There is a disorder called glutathione synthetase deficiency. This is what I found from Genetics Home Reference which is part of the National Institutes of Health. They had some interesting information. "Glutathione synthetase deficiency can be classified into three types: mild, moderate, and severe. Mild glutathione synthetase deficiency usually results in the destruction of red blood cells (hemolytic anemia)." (7)

"...individuals affected by the severe form of this disorder may experience neurological symptoms. These problems may include seizures; a generalized slowing down of physical reactions, movements, and speech (psychomotor retardation); intellectual disability; and a loss of coordination (ataxia). Some people with severe glutathione synthetase deficiency also develop recurrent bacterial infections." (7)

So from what I have learned there is a good chance that a severe and prolonged immune response from vaccination (physical stress/cytokine storm) has the potential to trigger this deficiency of glutathione. I wonder if any of the doctors are checking for this. Probably not.

I think what bothers me greatly is that we lay people have been able to connect higher levels of testosterone in young women and the side effects that are happening with the HPV vaccines. The other thing that we found was that these same side effects abound in the Autism community. Why is that I wonder? How is this linked to the depletion of glutathione?

In my next article I am going to focus on how this all works together with overweight females.

It is my hope that you are finding this information as interesting as we did when we put it all together for the FDA presentation.

If after reading this you want to do your own research into the HPV vaccines here are some places to start.

http://www.renewamerica.com/columns/janak

http://truthaboutgardasil.org

http://www.cynthiajanak.com/Gardasil.html

http://holyhormones.com

amenorrheic — Absent menstrual periods, either because of absent ovulation (anovulation) or because of absence of, destruction of, or obstruction to the menstrual flow from the uterus, such as with intrauterine adhesions (when it's known as Asherman's syndrome).

Hypothalamic — The hypothalamus is a portion of the brain that contains a number of small nuclei with a variety of functions. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis). The hypothalamus is responsible for certain metabolic processes and other activities of the Autonomic Nervous System. It synthesizes and secretes neurohormones, often called hypothalamic-releasing hormones, and these in turn stimulate or inhibit the secretion of pituitary hormones. The hypothalamus controls body temperature, hunger, thirst,[1] fatigue, and circadian cycles. http://en.wikipedia.org/wiki/Hypothalamus

oligomenorrheic — oligomenorrhea Infrequent menstrual periods. By convention, a menstrual cycle that is consistently longer than 35 days. Oligomenorrhea always reflects irregularity of hormonal events coming from the ovaries.


(1) Immunization Before the Next Pandemic? Risks, Benefits and Pathways, Jesse L. Goodman, MD, MPH Director, Center for Biologics Evaluation and Research, IDSA, Washington, DC, May 19,2008, http://www.fda.gov/downloads/BiologicsBloodVaccines/NewsEvents/WorkshopsMeetingsConferences/UCM102985.pdf

(2) KPC Archives, Researcher blasts HPV marketing, BY CINDY BEVINGTON, Published: Wednesday March 21, 2007, http://www.kpcnews.com/archives/legacy.php?id=99573

(3) Diurnal Profiles of Testosterone and Pituitary Hormones Suggest Different Mechanisms for Menstrual Disturbances in Endurance Athletes, The Journal of Clinical Endocrinology & Metabolism 89(2):702–707, Printed in U.S.A. Copyright © 2004 by The Endocrine Society, doi: 10.1210/jc.2003-030306

(4) "College Sports Scholarships," "The importance of hormones in female athletic competition," http://www.collegesportsscholarships.com/steroids-testosterone-women.htm

(5) Time, "A Link Between Autism and Testosterone?" by Eben Harrell, January 15th of 2009. http://www.time.com/time/health/article/0,8599,1871515,00.html

(6) The MAX site, Glutathione (pronounced 'gloota-thigh-own') is the body's essential health ABC's — Antioxidant, Blood Booster and Cell Detoxifier. http://www.themaxsite.com/glutathione.html

(7) Genetics Home Reference, Glutathione synthetase deficiency, Reviewed December 2006, http://ghr.nlm.nih.gov/condition/glutathione-synthetase-deficiency

© Cynthia A. Janak

 

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Cynthia A. Janak

Cynthia Janak is a freelance journalist, mother of three, foster mother of one, grandmother of five, business owner, Chamber of Commerce member... (more)

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